Mitral Regurgitation Là Gì


Mitral valve prolapse is a heart problem involving the mitral valve, which separates the upper and lower chambers of the left side of the heart. In this condition, the valve does not close normally.

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The mitral valve helps blood on the left side of the heart flow in one direction. It closes to lớn keep blood from moving backwards when the heart beats (contracts).

Mitral valve prolapse is the term used when the valve does not close properly. It can be caused by many different things.

In most cases, it is harmless. The problem generally does not affect health and most people with the condition are not aware of it. In a small number of cases, the prolapse can cause blood khổng lồ leak backwards. This is called mitral regurgitation.

Mitral valve prolapse often affects thin women who may have minor chest wall deformities, scoliosis, or other disorders. Some forms of mitral valve prolapse seem to be passed down through families (inherited).

Mitral valve prolapse is also seen with some connective tissue disorders such as Marfan syndrome và other rare genetic disorders.

It is also sometimes seen in isolation in people who are otherwise normal.



Many people with mitral valve prolapse bởi NOT have symptoms. A group of symptoms sometimes found in people with mitral valve prolapse has been called "mitral valve prolapse syndrome," và includes:

Chest pain (not caused by coronary artery disease or a heart attack)DizzinessFatiguePanic attacksShortness of breath with activity or when lying flat (orthopnea)

The exact relationship is between these symptoms and the valve problem is not clear. Some of the findings may be coincidental.

When mitral regurgitation occurs, symptoms may be related to the leaking, particularly when severe.

Exams và Tests

The health care provider will perform a physical exam and use a stethoscope to listen to your heart and lungs. The provider may feel a thrill (vibration) over the heart & hear a heart murmur and an extra sound (midsystolic click). The murmur usually gets longer & louder when you stand up.

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Blood pressure is most often normal.

Echocardiogram is the most common thử nghiệm used to diagnose mitral valve prolapse. The following tests may also be used to diagnose mitral valve prolapse or a leaky mitral valve or complications from those conditions:

Cardiac catheterizationChest x-rayECG (may show arrhythmias such as atrial fibrillation)MRI scan of the heart


Most of the time, there are few or no symptoms và treatment is not needed.

In the past, most people with heart valve problems were given antibiotics before dental work or procedures such as colonoscopy to prevent an infection in the heart. However, antibiotics are now used much less often. Check with your provider lớn see if you need antibiotics.

There are many heart medicines that may be used lớn treat aspects of this condition. However, most people will not need any treatment. You may need surgery lớn repair or replace your mitral valve if it becomes very leaky (regurgitation), and if the leakiness also causes symptoms. However, this may not occur. You may need mitral valve repair or replacement if:

Your symptoms get worse.The left ventricle of your heart is enlarged.Your heart function gets worse.

Outlook (Prognosis)

Most of the time, mitral valve prolapse is harmless & does not cause symptoms. Symptoms that vì occur can be treated and controlled with medicine or surgery.

Some abnormal heartbeats (arrhythmias) in people with mitral valve prolapse can be life threatening. If the valve leakage becomes severe, your outlook may be similar khổng lồ that of people who have mitral regurgitation from any other cause.

When to tương tác a Medical Professional

Call your provider if you have:

Chest discomfort, palpitations, or fainting spells that get worseLong-term illnesses with fevers

Alternative Names

Barlow syndrome; Floppy mitral valve; Myxomatous mitral valve; Billowing mitral valve; Systolic click-murmur syndrome; Prolapsing mitral leaflet syndrome; Chest pain - mitral valve prolapse

Patient Instructions



Carabello BA. Valvular heart disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 66.

Nishimura RA, Otto CM, Bonow RO, et al. 2017 AHA/ACC focused update of the năm trước AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2017;135(25):e1159-e1195. PMID: 28298458

Thomas JD, Bonow RO. Mitral valve disease. In: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald"s Heart Disease: A Textbook of Cardiovascular Medicine. 11th ed. Philadelphia, PA: Elsevier; 2019:chap 69.

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Updated by: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

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